Roles of thromboxane A(2) and prostacyclin in the development of atherosclerosis in apoE-deficient mice

Production of thromboxane (TX) A(2) and PG I(2)/prostacyclin (PGI(2)) is increased in patients with atherosclerosis. However, their roles in atherogenesis have not been critically defined. To examine this issue, we cross-bred atherosclerosis-prone apoE-deficient mice with mice deficient in either th...

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Main Authors: Kobayashi, Takuya, Tahara, Yoshio, Matsumoto, Mayumi, Iguchi, Masako, Sano, Hideto, Murayama, Toshinori, Arai, Hidenori, Oida, Hiroji, Yurugi-Kobayashi, Takami, Yamashita, Jun K., Katagiri, Hiroyuki, Majima, Masataka, Yokode, Masayuki, Kita, Toru, Narumiya, Shuh
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2004
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC516261/
https://ncbi.nlm.nih.gov/pubmed/15372102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200421446
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