Investigation of hydrophobic moment and hydrophobicity properties for transmembrane α-helices

Integral membrane proteins are the primary targets of novel drugs but are largely without solved structures. As a consequence, hydrophobic moment plot methodology is often used to identify putative transmembrane α-helices of integral membrane proteins, based on their local maximum mean hydrophobic m...

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Bibliografiske detaljer
Main Authors: Wallace, James, Daman, Onkabetse A, Harris, Frederick, Phoenix, David A
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2004
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC516255/
https://ncbi.nlm.nih.gov/pubmed/15312230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4682-1-5
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