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Off-Pathway Assembly of Fimbria Subunits Is Prevented by Chaperone CfaA of CFA/I Fimbriae from Enterotoxigenic E. coli

The assembly of the class 5 CFA/I fimbriae of enterotoxigenic E. coli was proposed to proceed via the alternate chaperone-usher pathway. Here, we show that in the absence of the chaperone CfaA, CfaB, the major pilin subunit of CFA/I fimbriae, is able to spontaneously refold and polymerize into cycli...

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Publicado en:Mol Microbiol
Autores principales: Bao, Rui, Liu, Yang, Savarino, Stephen J., Xia, Di
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5161713/
https://ncbi.nlm.nih.gov/pubmed/27627030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13530
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