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Mosquito larvicide BinAB revealed by de novo phasing with an X-ray laser

BinAB is a naturally occurring paracrystalline larvicide distributed worldwide to combat the devastating diseases borne by mosquitoes. These crystals are composed of homologous molecules, BinA and BinB, which play distinct roles in the multi-step intoxication process, transforming from harmless, rob...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Colletier, Jacques-Philippe, Sawaya, Michael R., Gingery, Mari, Rodriguez, Jose A., Cascio, Duilio, Brewster, Aaron S., Michels-Clark, Tara, Hice, Robert H., Coquelle, Nicolas, Boutet, Sébastien, Williams, Garth J., Messerschmidt, Marc, DePonte, Daniel P., Sierra, Raymond G., Laksmono, Hartawan, Koglin, Jason E., Hunter, Mark S., Park, Hyun-Woo, Uervirojnangkoorn, Monarin, Bideshi, Dennis K., Brunger, Axel T., Federici, Brian A., Sauter, Nicholas K., Eisenberg, David S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5161637/
https://ncbi.nlm.nih.gov/pubmed/27680699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature19825
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