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Oxidative diversification of amino acids and peptides by small-molecule iron catalysis
Secondary metabolites synthesized by nonribosomal peptide synthetases (NRPSs) display diverse and complex topologies and possess an impressive range of biological activities(1,2) Much of this diversity derives from a synthetic strategy that entails the oxidation of both the chiral amino acid buildin...
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Publicado no: | Nature |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5161617/ https://ncbi.nlm.nih.gov/pubmed/27479323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature18941 |
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