Progressing Bevacizumab-Induced Diffusion Restriction Is Associated with Coagulative Necrosis Surrounded by Viable Tumor and Decreased Overall Survival in Patients with Recurrent Glioblastoma

BACKGROUND AND PURPOSE: Patients with recurrent glioblastoma often exhibit regions of diffusion restriction following the initiation of bevacizumab therapy. Studies suggest that these regions represent either diffusion-restricted necrosis or hypercellular tumor. This study explored postmortem brain...

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Detalhes bibliográficos
Publicado no:AJNR Am J Neuroradiol
Main Authors: Nguyen, H.S., Milbach, N., Hurrell, S.L., Cochran, E., Connelly, J., Bovi, J.A., Schultz, C.J., Mueller, W.M., Rand, S.D., Schmainda, K.M., LaViolette, P.S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Neuroradiology 2016
Assuntos:
Adult Brain
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5161572/
https://ncbi.nlm.nih.gov/pubmed/27492073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3174/ajnr.A4898
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