FOXD1-ALDH1A3 signaling is a determinant for the self-renewal and tumorigenicity of mesenchymal glioma stem cells

Glioma stem-like cells (GSC) with tumor initiating activity orchestrate the cellular hierarchy in glioblastoma (GBM) and engender therapeutic resistance. Recent work has divided GSC into two subtypes with a mesenchymal (MES) GSC population as the more malignant subtype. In this study, we identify th...

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Publicado en:Cancer Res
Autores principales: Cheng, Peng, Wang, Jia, Waghmare, Indrayani, Sartini, Stefania, Coviello, Vito, Zhang, Zhuo, Kim, Sung-Hak, Mohyeldin, Ahmed, Pavlyukov, Marat S., Minata, Mutsuko, Valentim, Claudia L. L., Chhipa, Rishi Raj, Bhat, Krishna P.L., Dasgupta, Biplab, La Motta, Concettina, Kango-Singh, Madhuri, Nakano, Ichiro
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5161538/
https://ncbi.nlm.nih.gov/pubmed/27569208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-2860
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