Inferring Aggregated Functional Traits from Metagenomic Data Using Constrained Non-negative Matrix Factorization: Application to Fiber Degradation in the Human Gut Microbiota

Whole Genome Shotgun (WGS) metagenomics is increasingly used to study the structure and functions of complex microbial ecosystems, both from the taxonomic and functional point of view. Gene inventories of otherwise uncultured microbial communities make the direct functional profiling of microbial co...

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Detalles Bibliográficos
Publicado en:PLoS Comput Biol
Main Authors: Raguideau, Sébastien, Plancade, Sandra, Pons, Nicolas, Leclerc, Marion, Laroche, Béatrice
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5161307/
https://ncbi.nlm.nih.gov/pubmed/27984592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005252
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