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Inferring Aggregated Functional Traits from Metagenomic Data Using Constrained Non-negative Matrix Factorization: Application to Fiber Degradation in the Human Gut Microbiota

Whole Genome Shotgun (WGS) metagenomics is increasingly used to study the structure and functions of complex microbial ecosystems, both from the taxonomic and functional point of view. Gene inventories of otherwise uncultured microbial communities make the direct functional profiling of microbial co...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Raguideau, Sébastien, Plancade, Sandra, Pons, Nicolas, Leclerc, Marion, Laroche, Béatrice
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5161307/
https://ncbi.nlm.nih.gov/pubmed/27984592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005252
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