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Hormonal modulation of a gene injected into rat heart in vivo.

We demonstrate gene transfer into rat heart in vivo by the direct injection of plasmid DNA. Injection of gene constructs driven by retroviral and cellular promoters resulted in detectable levels of reporter gene activities. The cellular promoter and 5' flanking sequence (positions -613 to +32) were...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Kitsis, R N, Buttrick, P M, McNally, E M, Kaplan, M L, Leinwand, L A
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1991
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51613/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2034660/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.10.4138
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