Metabolic profiling indicates impaired pyruvate dehydrogenase function in myalgic encephalopathy/chronic fatigue syndrome

Myalgic encephalopathy/chronic fatigue syndrome (ME/CFS) is a debilitating disease of unknown etiology, with hallmark symptoms including postexertional malaise and poor recovery. Metabolic dysfunction is a plausible contributing factor. We hypothesized that changes in serum amino acids may disclose...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Fluge, Øystein, Mella, Olav, Bruland, Ove, Risa, Kristin, Dyrstad, Sissel E., Alme, Kine, Rekeland, Ingrid G., Sapkota, Dipak, Røsland, Gro V., Fosså, Alexander, Ktoridou-Valen, Irini, Lunde, Sigrid, Sørland, Kari, Lien, Katarina, Herder, Ingrid, Thürmer, Hanne, Gotaas, Merete E., Baranowska, Katarzyna A., Bohnen, Louis M.L.J., Schäfer, Christoph, McCann, Adrian, Sommerfelt, Kristian, Helgeland, Lars, Ueland, Per M., Dahl, Olav, Tronstad, Karl J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5161229/
https://ncbi.nlm.nih.gov/pubmed/28018972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.89376
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