Interlesional diversity of T cell receptors in melanoma with immune checkpoints enriched in tissue-resident memory T cells

Heterogeneity of tumor cells and their microenvironment can affect outcome in cancer. Blockade of immune checkpoints (ICPs) expressed only on a subset of immune cells leads to durable responses in advanced melanoma. Tissue-resident memory T (T(RM)) cells have recently emerged as a distinct subset of...

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Опубликовано в: :JCI Insight
Главные авторы: Boddupalli, Chandra Sekhar, Bar, Noffar, Kadaveru, Krishna, Krauthammer, Michael, Pornputtapong, Natopol, Mai, Zifeng, Ariyan, Stephan, Narayan, Deepak, Kluger, Harriet, Deng, Yanhong, Verma, Rakesh, Das, Rituparna, Bacchiocchi, Antonella, Halaban, Ruth, Sznol, Mario, Dhodapkar, Madhav V., Dhodapkar, Kavita M.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2016
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5161225/
https://ncbi.nlm.nih.gov/pubmed/28018970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.88955
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