Interlesional diversity of T cell receptors in melanoma with immune checkpoints enriched in tissue-resident memory T cells

Heterogeneity of tumor cells and their microenvironment can affect outcome in cancer. Blockade of immune checkpoints (ICPs) expressed only on a subset of immune cells leads to durable responses in advanced melanoma. Tissue-resident memory T (T(RM)) cells have recently emerged as a distinct subset of...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Boddupalli, Chandra Sekhar, Bar, Noffar, Kadaveru, Krishna, Krauthammer, Michael, Pornputtapong, Natopol, Mai, Zifeng, Ariyan, Stephan, Narayan, Deepak, Kluger, Harriet, Deng, Yanhong, Verma, Rakesh, Das, Rituparna, Bacchiocchi, Antonella, Halaban, Ruth, Sznol, Mario, Dhodapkar, Madhav V., Dhodapkar, Kavita M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5161225/
https://ncbi.nlm.nih.gov/pubmed/28018970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.88955
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