Integrated, multicohort analysis of systemic sclerosis identifies robust transcriptional signature of disease severity

Systemic sclerosis (SSc) is a rare autoimmune disease with the highest case-fatality rate of all connective tissue diseases. Current efforts to determine patient response to a given treatment using the modified Rodnan skin score (mRSS) are complicated by interclinician variability, confounding, and...

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Pubblicato in:JCI Insight
Autori principali: Lofgren, Shane, Hinchcliff, Monique, Carns, Mary, Wood, Tammara, Aren, Kathleen, Arroyo, Esperanza, Cheung, Peggie, Kuo, Alex, Valenzuela, Antonia, Haemel, Anna, Wolters, Paul J., Gordon, Jessica, Spiera, Robert, Assassi, Shervin, Boin, Francesco, Chung, Lorinda, Fiorentino, David, Utz, Paul J., Whitfield, Michael L., Khatri, Purvesh
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5161207/
https://ncbi.nlm.nih.gov/pubmed/28018971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.89073
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