Expression from the murine p53 promoter is mediated by factor binding to a downstream helix-loop-helix recognition motif.
Expression of the p53 gene plays an important role in the regulation of cellular proliferation and malignant transformation. Overexpression of mutant forms of p53 is in fact a common feature of many transformed cells. Studies dealing with the transcriptional regulatory regions of the p53 gene indica...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1991
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51611/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1851994/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.10.4128 |
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