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Idelalisib in the management of lymphoma

Inhibition of the phosphatidylinositol-3-kinase (PI3K) pathway as an anticancer therapeutic strategy was realized with the approval of the orally bioavailable small molecule PI3Kδ inhibitor idelalisib. In this focused review, we highlight the rationale for targeting the pathway in lymphomas, provide...

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Bibliografske podrobnosti
izdano v:Blood
Main Authors: Cheah, Chan Yoon, Fowler, Nathan H.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5161010/
https://ncbi.nlm.nih.gov/pubmed/27252232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-02-702761
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