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Attenuation of pathogenic Rift Valley fever virus strain through the chimeric S-segment encoding sandfly fever phlebovirus NSs or a dominant-negative PKR

Rift Valley fever is a mosquito-borne zoonotic disease affecting ruminants and humans. Rift Valley fever virus (RVFV: family Bunyaviridae, genus Phlebovirus) causes abortions and fetal malformations in ruminants, and hemorrhagic fever, encephalitis, or retinitis in humans. The live-attenuated MP-12...

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Detalhes bibliográficos
Publicado no:Virulence
Main Authors: Nishiyama, Shoko, Slack, Olga A. L., Lokugamage, Nandadeva, Hill, Terence E., Juelich, Terry L., Zhang, Lihong, Smith, Jennifer K., Perez, David, Gong, Bin, Freiberg, Alexander N., Ikegami, Tetsuro
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5160418/
https://ncbi.nlm.nih.gov/pubmed/27248570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21505594.2016.1195528
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