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Pleiotrophin is a driver of vascular abnormalization in glioblastoma

In a recent report by Zhang et al., pleiotrophin (PTN) was demonstrated to enhance glioma growth by promoting vascular abnormalization. PTN stimulates glioma vessels through anaplastic lymphoma kinase (Alk)-mediated perivascular deposition of vascular endothelial growth factor (VEGF). Targeting of A...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Zhang, Lei, Dimberg, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5160416/
https://ncbi.nlm.nih.gov/pubmed/28090572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2016.1141087
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