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Effects of Filipin on the Structure and Biological Activity of Enveloped Viruses

The interaction of the polyene antibiotic filipin with membrane-bound cholesterol in vesicular stomatitis (VS), influenza, and Rauscher leukemia virions was studied. Exposure of virions to filipin resulted in a series of depressions and ridges in the envelope of VS virions, with a periodicity of 15...

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Main Authors: Majuk, Zenowij, Bittman, Robert, Landsberger, Frank R., Compans, Richard W.
Formato: Artigo
Idioma:Inglês
Publicado: 1977
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC516010/
https://ncbi.nlm.nih.gov/pubmed/201781
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