Pharmacological and genetic reappraisals of protease and oxidative stress pathways in a mouse model of obstructive lung diseases

Protease-antiprotease imbalance and oxidative stress are considered to be major pathophysiological hallmarks of severe obstructive lung diseases including chronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF), but limited information is available on their direct roles in the regulati...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Shuto, Tsuyoshi, Kamei, Shunsuke, Nohara, Hirofumi, Fujikawa, Haruka, Tasaki, Yukihiro, Sugahara, Takuya, Ono, Tomomi, Matsumoto, Chizuru, Sakaguchi, Yuki, Maruta, Kasumi, Nakashima, Ryunosuke, Kawakami, Taisei, Suico, Mary Ann, Kondo, Yoshitaka, Ishigami, Akihito, Takeo, Toru, Tanaka, Ken-ichiro, Watanabe, Hiroshi, Nakagata, Naomi, Uchimura, Kohei, Kitamura, Kenichiro, Li, Jian-Dong, Kai, Hirofumi
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159865/
https://ncbi.nlm.nih.gov/pubmed/27982104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39305
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