Pharmacological and genetic reappraisals of protease and oxidative stress pathways in a mouse model of obstructive lung diseases

Protease-antiprotease imbalance and oxidative stress are considered to be major pathophysiological hallmarks of severe obstructive lung diseases including chronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF), but limited information is available on their direct roles in the regulati...

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Publicado no:Sci Rep
Main Authors: Shuto, Tsuyoshi, Kamei, Shunsuke, Nohara, Hirofumi, Fujikawa, Haruka, Tasaki, Yukihiro, Sugahara, Takuya, Ono, Tomomi, Matsumoto, Chizuru, Sakaguchi, Yuki, Maruta, Kasumi, Nakashima, Ryunosuke, Kawakami, Taisei, Suico, Mary Ann, Kondo, Yoshitaka, Ishigami, Akihito, Takeo, Toru, Tanaka, Ken-ichiro, Watanabe, Hiroshi, Nakagata, Naomi, Uchimura, Kohei, Kitamura, Kenichiro, Li, Jian-Dong, Kai, Hirofumi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159865/
https://ncbi.nlm.nih.gov/pubmed/27982104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39305
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