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Serotonergic neuronal death and concomitant serotonin deficiency curb copulation ability of Drosophila platonic mutants

Drosophila platonic (plt) males court females, but fail to copulate. Here we show that plt is an allele of scribbler (sbb), a BMP signalling component. sbb knockdown in larvae leads to the loss of approximately eight serotonergic neurons, which express the sex-determinant protein Doublesex (Dsx). Ge...

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Udgivet i:Nat Commun
Main Authors: Yilmazer, Yasemin B., Koganezawa, Masayuki, Sato, Kosei, Xu, Jinhua, Yamamoto, Daisuke
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159827/
https://ncbi.nlm.nih.gov/pubmed/27958269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13792
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