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Gene expression in local stroma reflects breast tumor states and predicts patient outcome

The surrounding microenvironment has been implicated in the progression of breast tumors to metastasis. However, the degree to which metastatic breast tumors locally reprogram stromal cells as they disrupt tissue boundaries is not well understood. We used species-specific RNA sequencing in a mouse x...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Bainer, Russell, Frankenberger, Casey, Rabe, Daniel, An, Gary, Gilad, Yoav, Rosner, Marsha Rich
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159815/
https://ncbi.nlm.nih.gov/pubmed/27982086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39240
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