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iciA, an Escherichia coli gene encoding a specific inhibitor of chromosomal initiation of replication in vitro.

The gene encoding the protein that binds the three 13-mers in the origin (oriC) of Escherichia coli to block initiation of replication in vitro has been cloned, sequenced, and overexpressed. The gene possesses an open reading frame for 297 amino acids (mass of 33,471 Da). The protein has a motif for...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Thöny, B, Hwang, D S, Fradkin, L, Kornberg, A
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1991
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51598/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2034653/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.10.4066
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