tRNA anticodon loop modifications ensure protein homeostasis and cell morphogenesis in yeast

Using budding yeast, we investigated a negative interaction network among genes for tRNA modifications previously implicated in anticodon-codon interaction: 5-methoxy-carbonyl-methyl-2-thio-uridine (mcm(5)s(2)U34: ELP3, URM1), pseudouridine (Ψ38/39: DEG1) and cyclic N6-threonyl-carbamoyl-adenosine (...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Klassen, Roland, Ciftci, Akif, Funk, Johanna, Bruch, Alexander, Butter, Falk, Schaffrath, Raffael
Format: Artigo
Language:Inglês
Published: Oxford University Press 2016
Subjects:
RNA
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159529/
https://ncbi.nlm.nih.gov/pubmed/27496282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw705
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