Identification of Iguratimod as an Inhibitor of Macrophage Migration Inhibitory Factor (MIF) with Steroid-sparing Potential

Macrophage migration inhibitory factor (MIF) is a pleiotropic cytokine that has been implicated in a broad range of inflammatory and oncologic diseases. MIF is unique among cytokines in terms of its release profile and inflammatory role, notably as an endogenous counter-regulator of the anti-inflamm...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Bloom, Joshua, Metz, Christine, Nalawade, Saisha, Casabar, Julian, Cheng, Kai Fan, He, Mingzhu, Sherry, Barbara, Coleman, Thomas, Forsthuber, Thomas, Al-Abed, Yousef
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2016
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159510/
https://ncbi.nlm.nih.gov/pubmed/27793992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.743328
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