Serine/Arginine-rich Splicing Factor 2 Modulates Herpes Simplex Virus Type 1 Replication via Regulating Viral Gene Transcriptional Activity and Pre-mRNA Splicing

Once it enters the host cell, herpes simplex virus type 1 (HSV-1) recruits a series of host cell factors to facilitate its life cycle. Here, we demonstrate that serine/arginine-rich splicing factor 2 (SRSF2), which is an important component of the splicing speckle, mediates HSV-1 replication by regu...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Wang, Ziqiang, Liu, Qing, Lu, Jinhua, Fan, Ping, Xie, Weidong, Qiu, Wei, Wang, Fan, Hu, Guangnan, Zhang, Yaou
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159499/
https://ncbi.nlm.nih.gov/pubmed/27784784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.753046
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