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Hypo-methylation of CYP11B2 in aldosterone-producing adenoma

The purpose of this study was to evaluate the DNA methylation levels of steroidogenic enzyme genes in aldosterone-producing adenoma (APA), and the effects of gene mutations in APA on the DNA methylation levels. DNA methylation array analysis was conducted using non-functioning adrenocortical adenoma...

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Publicat a:Hypertension
Autors principals: Yoshii, Yoko, Oki, Kenji, Gomez-Sanchez, Celso E, Ohno, Haruya, Itcho, Kiyotaka, Kobuke, Kazuhiro, Yoneda, Masayasu
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159261/
https://ncbi.nlm.nih.gov/pubmed/27754862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.116.08313
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