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Selective Deletion of the Brain-Specific Isoform of Renin Causes Neurogenic Hypertension
The renin-angiotensin system (RAS) in the brain is a critical determinant of blood pressure but the mechanisms regulating RAS activity in the brain remain unclear. Expression of brain renin (renin-b) occurs from an alternative promoter-first exon. The predicted translation product is a non-secreted...
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| Udgivet i: | Hypertension |
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| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5159235/ https://ncbi.nlm.nih.gov/pubmed/27754863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.116.08242 |
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