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Enhanced Expression of Trib3 during the Development of Myelin Breakdown in dmy Myelin Mutant Rats

The demyelination (dmy) rat exhibits hind limb ataxia and severe myelin breakdown in the central nervous system. The causative gene of dmy rats is the MRS2 magnesium transporter gene. Tribbles homolog 3 (Trib3) is a pseudokinase molecule that modifies certain signal pathways, and its expression is i...

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Publicado en:PLoS One
Autores principales: Shimotsuma, Yukako, Tanaka, Miyuu, Izawa, Takeshi, Yamate, Jyoji, Kuwamura, Mitsuru
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5158197/
https://ncbi.nlm.nih.gov/pubmed/27977799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0168250
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