Characterization and Functional Analysis of Extracellular Vesicles and Muscle-Abundant miRNAs (miR-1, miR-133a, and miR-206) in C(2)C(12) Myocytes and mdx Mice

Duchenne muscular dystrophy (DMD) is a progressive neuromuscular disorder. Here, we show that the CD63 antigen, which is located on the surface of extracellular vesicles (EVs), is associated with increased levels of muscle-abundant miRNAs, namely myomiRs miR-1, miR-133a, and miR-206, in the sera of...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Matsuzaka, Yasunari, Tanihata, Jun, Komaki, Hirofumi, Ishiyama, Akihiko, Oya, Yasushi, Rüegg, Urs, Takeda, Shin-ichi, Hashido, Kazuo
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5158003/
https://ncbi.nlm.nih.gov/pubmed/27977725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167811
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