Determinants of Divergent Adaptive Immune Responses after Airway Sensitization with Ligands of Toll-Like Receptor 5 or Toll-Like Receptor 9

Excessive type 2 helper T cell responses to environmental antigens can cause immunopathology such as asthma and allergy, but how such immune responses are induced remains unclear. We studied this process in the airways by immunizing mice intranasally with the antigen ovalbumin together with either o...

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Udgivet i:PLoS One
Main Authors: Lee, Linda M., Ji, Ming, Sinha, Meenal, Dong, Matthew B., Ren, Xin, Wang, Yanli, Lowell, Clifford A., Ghosh, Sankar, Locksley, Richard M., DeFranco, Anthony L.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5157987/
https://ncbi.nlm.nih.gov/pubmed/27977701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167693
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