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Universal or Specific? A Modeling-Based Comparison of Broad-Spectrum Influenza Vaccines against Conventional, Strain-Matched Vaccines

Despite the availability of vaccines, influenza remains a major public health challenge. A key reason is the virus capacity for immune escape: ongoing evolution allows the continual circulation of seasonal influenza, while novel influenza viruses invade the human population to cause a pandemic every...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Subramanian, Rahul, Graham, Andrea L., Grenfell, Bryan T., Arinaminpathy, Nimalan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5157952/
https://ncbi.nlm.nih.gov/pubmed/27977667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005204
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