NMDARs Adapt to Neurotoxic HIV Protein Tat Downstream of a GluN2A–Ubiquitin Ligase Signaling Pathway

HIV-associated neurocognitive disorder (HAND) affects approximately half of HIV-infected patients. Infected non-neuronal cells release neurotoxic factors such as the viral protein transactivator of transcription (Tat) that potentiate NMDAR function. NMDARs regulate synaptic changes observed after ex...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Green, Matthew V., Thayer, Stanley A.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2016
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5157108/
https://ncbi.nlm.nih.gov/pubmed/27810933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2980-16.2016
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