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TRPV4 participates in pressure‐induced inhibition of renin secretion by juxtaglomerular cells

KEY POINTS: Increase in blood pressure in the renal afferent arteriole is known to induce an increase in cytosolic calcium concentration ([Ca(2+)](i)) of juxtaglomerular (JG) cells and to result in a decreased secretion of renin. Mechanical stimulation of As4.1 JG cells induces an increase in [Ca(2+...

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Detalhes bibliográficos
Publicado no:J Physiol
Main Authors: Seghers, François, Yerna, Xavier, Zanou, Nadège, Devuyst, Olivier, Vennekens, Rudi, Nilius, Bernd, Gailly, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5157090/
https://ncbi.nlm.nih.gov/pubmed/27779758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP273595
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