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Clinical implications of repeated drug monitoring of imatinib in patients with metastatic gastrointestinal stromal tumour

BACKGROUND: Imatinib mesylate (IM) is the preferred treatment for the majority of patients with metastatic gastrointestinal stromal tumour (GIST). Low trough IM concentration (C(min)) values have been associated with poor clinical outcomes in GIST patients. However, there are few studies of repeated...

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Detalhes bibliográficos
Publicado no:Clin Sarcoma Res
Main Authors: Hompland, Ivar, Bruland, Øyvind Sverre, Ubhayasekhera, Kumari, Bergquist, Jonas, Boye, Kjetil
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5157085/
https://ncbi.nlm.nih.gov/pubmed/27999655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13569-016-0062-2
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