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Cumulative subgroup analysis to reduce waste in clinical research for individualised medicine

BACKGROUND: Although subgroup analyses in clinical trials may provide evidence for individualised medicine, their conduct and interpretation remain controversial. METHODS: Subgroup effect can be defined as the difference in treatment effect across patient subgroups. Cumulative subgroup analysis refe...

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Bibliografiske detaljer
Udgivet i:BMC Med
Main Authors: Song, Fujian, Bachmann, Max O.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5157082/
https://ncbi.nlm.nih.gov/pubmed/27974045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-016-0744-x
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