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Selective accumulation of biotin in arterial chemoreceptors: requirement for carotid body exocytotic dopamine secretion

KEY POINTS: Biotin, a vitamin whose main role is as a coenzyme for carboxylases, accumulates at unusually large amounts within cells of the carotid body (CB). In biotin‐deficient rats biotin rapidly disappears from the blood; however, it remains at relatively high levels in CB glomus cells. The CB c...

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Détails bibliographiques
Publié dans:J Physiol
Auteurs principaux: Ortega‐Sáenz, Patricia, Macías, David, Levitsky, Konstantin L., Rodríguez‐Gómez, José A., González‐Rodríguez, Patricia, Bonilla‐Henao, Victoria, Arias‐Mayenco, Ignacio, López‐Barneo, José
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5157066/
https://ncbi.nlm.nih.gov/pubmed/27570189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP272961
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