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Genetically manipulated phages with improved pH resistance for oral administration in veterinary medicine

Orally administered phages to control zoonotic pathogens face important challenges, mainly related to the hostile conditions found in the gastrointestinal tract (GIT). These include temperature, salinity and primarily pH, which is exceptionally low in certain compartments. Phage survival under these...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Nobrega, Franklin L., Costa, Ana Rita, Santos, José F., Siliakus, Melvin F., van Lent, Jan W. M., Kengen, Servé W. M., Azeredo, Joana, Kluskens, Leon D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5157022/
https://ncbi.nlm.nih.gov/pubmed/27976713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39235
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