Microcystin-Leucine Arginine Causes Cytotoxic Effects in Sertoli Cells Resulting in Reproductive Dysfunction in Male Mice

Microcystin-leucine arginine (MC-LR) is a potent toxin for Sertoli cells. However, the specific molecular mechanisms of MC-induced cytotoxicity still remain unclear. In this study, we performed a comprehensive analyses of changes of miRNAs and mRNAs in Sertoli cells treated with MC-LR. Through compu...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Chen, Yabing, Zhou, Yuan, Wang, Jing, Wang, Lihui, Xiang, Zou, Li, Dongmei, Han, Xiaodong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5157014/
https://ncbi.nlm.nih.gov/pubmed/27976743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39238
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