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Inhibition of viral RNA methylation in herpes simplex virus type 1-infected cells by 5' S-isobutyl-adenosine.

5' S-isobutyl-adenosine (SIBA), a structural analogue of S-adenosylhomocysteine, reversibly blocks the multiplication of herpes simplex type 1 virus. In the presence of SIBA, viral protein synthesis is inhibited. After removing SIBA the synthesis of proteins starts rapidly again. The new polype...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Jacquemont, B, Huppert, J
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1977
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC515696/
https://ncbi.nlm.nih.gov/pubmed/192910
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