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Towards the atomic structure of the Nuclear Pore Complex: When top down meets bottom up

Elucidating the structure of the nuclear pore complex (NPC) is a prerequisite for understanding the molecular mechanism of nucleocytoplasmic transport. However, due to sheer size and flexibility, the NPC is unapproachable by classical structure determination techniques and requires a joint effort of...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Nat Struct Mol Biol
Main Authors: Hoelz, André, Glavy, Joseph S., Beck, Martin
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5156573/
https://ncbi.nlm.nih.gov/pubmed/27273515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3244
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