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Phosphatidylinositol 4-kinase IIβ negatively regulates invadopodia formation and suppresses an invasive cellular phenotype

The type II phosphatidylinositol 4-kinase (PI4KII) enzymes synthesize the lipid phosphatidylinositol 4-phosphate (PI(4)P), which has been detected at the Golgi complex and endosomal compartments and recruits clathrin adaptors. Despite common mechanistic similarities between the isoforms, the extent...

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Pubblicato in:Mol Biol Cell
Autori principali: Alli-Balogun, Ganiyu Olabanji, Gewinner, Christina A., Jacobs, Ruth, Kriston-Vizi, Janos, Waugh, Mark G., Minogue, Shane
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5156544/
https://ncbi.nlm.nih.gov/pubmed/27798239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-08-0564
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