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A Period of Controlled Elevation of IOP (CEI) Produces the Specific Gene Expression Responses and Focal Injury Pattern of Experimental Rat Glaucoma

PURPOSE: We determine if several hours of controlled elevation of IOP (CEI) will produce the optic nerve head (ONH) gene expression changes and optic nerve (ON) damage pattern associated with early experimental glaucoma in rats. METHODS: The anterior chambers of anesthetized rats were cannulated and...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Morrison, John C., Cepurna, William O., Tehrani, Shandiz, Choe, Tiffany E., Jayaram, Hari, Lozano, Diana C., Fortune, Brad, Johnson, Elaine C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5156512/
https://ncbi.nlm.nih.gov/pubmed/27942722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-20573
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