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Patient-Specific Screening Using High-Grade Glioma Explants to Determine Potential Radiosensitization by a TGF-β Small Molecule Inhibitor()()
High-grade glioma (HGG), a deadly primary brain malignancy, manifests radioresistance mediated by cell-intrinsic and microenvironmental mechanisms. High levels of the cytokine transforming growth factor-β (TGF-β) in HGG promote radioresistance by enforcing an effective DNA damage response and suppor...
שמור ב:
| הוצא לאור ב: | Neoplasia |
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| Main Authors: | , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Neoplasia Press
2016
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5156509/ https://ncbi.nlm.nih.gov/pubmed/27978994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2016.08.008 |
| תגים: |
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