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The In Vitro Effect of Acidic-Pepsin on Nuclear Factor KappaB Activation and Its Related Oncogenic Effect on Normal Human Hypopharyngeal Cells

BACKGROUND: Extra-esophageal carcinogenesis has been widely discussed in relation to the chronic effects of laryngopharyngeal reflux and most prominently with pepsin historically central to this discussion. With refluxate known to include gastric (pepsin) and duodenal (bile) fluids, we recently demo...

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Foilsithe in:PLoS One
Main Authors: Sasaki, Clarence T., Toman, Julia, Vageli, Dimitra
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5156414/
https://ncbi.nlm.nih.gov/pubmed/27973541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0168269
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