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Bicarbonate Increases Ischemia-Reperfusion Damage by Inhibiting Mitophagy

During an ischemic event, bicarbonate and CO(2) concentration increase as a consequence of O(2) consumption and lack of blood flow. This event is important as bicarbonate/CO(2) is determinant for several redox and enzymatic reactions, in addition to pH regulation. Until now, most work done on the ro...

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Bibliographic Details
Published in:PLoS One
Main Authors: Queliconi, Bruno B., Kowaltowski, Alicia J., Gottlieb, Roberta A.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5156406/
https://ncbi.nlm.nih.gov/pubmed/27973540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167678
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