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Evidence that nerve growth factor dependence of sympathetic neurons for survival in vitro may be determined by levels of cytoplasmic free Ca2+.

Developing sympathetic neurons established in the presence of nerve growth factor (NGF) die in vitro after acute withdrawal of NGF. This in vitro model mimics the physiological situation in which neurons die during development or after axotomy when trophic support becomes insufficient. We have previ...

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Detalhes bibliográficos
Main Authors: Koike, T, Tanaka, S
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC51559/
https://ncbi.nlm.nih.gov/pubmed/2023936
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