Differences in Mitochondrial Coupling Reveal a Novel Signature of Mitohormesis in Muscle of Healthy Individuals

CONTEXT: Reduced mitochondrial coupling (ATP/O(2) [P/O]) is associated with sedentariness and insulin resistance. Interpreting the physiological relevance of P/O measured in vitro is challenging. OBJECTIVE: To evaluate muscle mitochondrial function and associated transcriptional profiles in nonobese...

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Detalhes bibliográficos
Publicado no:J Clin Endocrinol Metab
Main Authors: Sparks, Lauren M., Redman, Leanne M., Conley, Kevin E., Harper, Mary-Ellen, Hodges, Andrew, Eroshkin, Alexey, Costford, Sheila R., Gabriel, Meghan E., Yi, Fanchao, Shook, Cherie, Cornnell, Heather H., Ravussin, Eric, Smith, Steven R.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2016
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5155692/
https://ncbi.nlm.nih.gov/pubmed/27710240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2016-2742
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