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The identification of hematopoietic-specific regulatory elements for WASp gene expression

Chromosome Conformation Capture (3C) technology was used to identify physical interactions between the proximal Wiskott-Aldrich Syndrome protein (WASp) promoter and its distant DNA segments in Jurkat-T cells. We found that two hematopoietic specific DNase I hypersensitive (DHS) sites (proximal DHS-A...

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Detalhes bibliográficos
Publicado no:Mol Ther Methods Clin Dev
Main Authors: Zhan, Jun, Johnson, Irudayam Maria, Wielgosz, Matthew, Nienhuis, Arthur W
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5155633/
https://ncbi.nlm.nih.gov/pubmed/28035317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2016.77
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