Divergent Synthesis of Chondroitin Sulfate Disaccharides and Identification of Sulfate Motifs that Inhibit Triple Negative Breast Cancer

Glycosaminoglycans (GAGs) regulate many important physiological processes. A pertinent issue to address is whether GAGs encode important functional information via introduction of position specific sulfate groups in the GAG structure. However, procurement of pure, homogenous GAG motifs to probe the...

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Udgivet i:Sci Rep
Main Authors: Wei Poh, Zhong, Heng Gan, Chin, Lee, Eric J., Guo, Suxian, Yip, George W., Lam, Yulin
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5155627/
https://ncbi.nlm.nih.gov/pubmed/26400608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14355
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